| Identification | Back Directory | [Name]
AC-LYS-PRO-VAL-NH2 | [CAS]
57899-96-4 | [Synonyms]
α-MSH(11-13)
AC-LYS-PRO-VAL-NH2
Acetyl-a-MSH-(11-13
AC-ALPHA-MSH (11-13)
Acetyl-α-MSH (11-13)
N-AC-LYS-PRO-VAL-NH2
ACETYL-ALPHA-MSH (11-13)
N-acetyllysyl-prolyl-valinamide
Acetyl-α-MSH (11-13) hydrochloride salt
L-Valinamide, N2-acetyl-L-lysyl-L-prolyl-
Acetyl-alpha-MSH (11-13) hydrochloride salt
(2S)-2-acetamido-6-amino-N-[(2S)-2-amino-3-methylbutanoyl]-N-propylhexanamide
(S)-1-((S)-2-Acetamido-6-aminohexanoyl)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)pyrrolidine-2-carboxamide | [Molecular Formula]
C18H33N5O4 | [MDL Number]
MFCD00237182 | [MOL File]
57899-96-4.mol | [Molecular Weight]
383.49 |
| Chemical Properties | Back Directory | [Boiling point ]
743.9±60.0 °C(Predicted) | [density ]
1.170±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C
| [pka]
13.44±0.20(Predicted) | [Sequence]
Ac-Lys-Pro-Val-NH2 |
| Hazard Information | Back Directory | [Uses]
Acetyl-α-MSH (11-13) is the acetylated C-terminal tripeptide of α-MSH with antipyretic and anti-inflammatory activities[1][2]. | [References]
[1] Schi?th HB, et al. New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone. Basic Clin Pharmacol Toxicol. 2006 Oct;99(4):287-93. DOI:10.1111/j.1742-7843.2006.pto_459.x
[2] Shimizu H, et al. Alpha-melanocyte-stimulating hormone (MSH) inhibits insulin secretion in HIT-T 15 cells. Peptides. 1995;16(4):605-8.Shimizu H, et al. Alpha-melanocyte-stimulating hormone (MSH) inhibits insulin secretion in HIT-T 15 cells. Peptides. 1995;16(4):605-8. DOI:10.1016/0196-9781(94)00197-e |
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