| Identification | Back Directory | [Name]
cyclovalone | [CAS]
579-23-7 | [Synonyms]
Flavugal
Vanilone
cyqualon
Aids057932
Aids-057932
cyclovalone
Cyclovalonum
Divanillydene cyclohexanone
DIVANILLYLIDENECYCLOHEXANONE
2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexanone
2,6-Bis(4-hydroxy-3-methoxybenzylidene)cyclohexan-1-one
Cyclohexanone, 2,6-bis[(4-hydroxy-3-methoxyphenyl)methylene]-
2,6-Bis((4-hydroxy-3-methoxyphenyl)methylene)cyclohexan-1-one | [EINECS(EC#)]
209-438-9 | [Molecular Formula]
C22H22O5 | [MDL Number]
MFCD00019515 | [MOL File]
579-23-7.mol | [Molecular Weight]
366.41 |
| Chemical Properties | Back Directory | [Melting point ]
178-179° | [Boiling point ]
595.5±50.0 °C(Predicted) | [density ]
1.292±0.06 g/cm3(Predicted) | [solubility ]
Acetone (Slightly, Sonicated), DMSO (Slightly) | [form ]
Solid | [pka]
9.44±0.35(Predicted) | [color ]
Yellow to Very Dark Yellow | [Stability:]
Light Sensitive | [LogP]
4.470 (est) |
| Hazard Information | Back Directory | [Uses]
2,6-Divanillylidenecyclohexanone (cas# 579-23-7) is used to make a nanofiber which is found to have anti-bacterial and anti-cancer activity. | [Definition]
ChEBI: Cyclovalone is a diarylheptanoid. | [in vivo]
Cyclovalone (9.5-38 mg/kg, p.o. for 14 days) ist a prostate specific antagonist without significant toxicity in BALB/c mice[2]. | Animal Model: | BALB/c mice[2] | | Dosage: | 9.5-38 mg/kg/day | | Administration: | p.o. for 14 days | | Result: | Reduced weight of ventral prostate in a dose-dependent manner. |
| Animal Model: | PC-3 xenografted athymic BALB/c nude mice[2] | | Dosage: | 38 mg/kg | | Administration: | p.o. for 20 days | | Result: | Inhibited tumor growth without toxicity. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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