| | Identification | Back Directory |  | [Name] 
 Cafedrine
 |  | [CAS] 
 58166-83-9
 |  | [Synonyms] 
 Cafedrine
 Cafedrina
 Brn 0583473
 (-)-Cafedrine
 Cafedrina [inn-spanish]
 7-(2-(2-Hydroxy-1-methylphenethylamino)ethyl)theophylline
 7-(2-(beta-Hydroxy-alpha-methylphenethylamino)ethyl)theophylline
 7-[2-(β-Hydroxy-α-methylphenethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
 3,7-Dihydro-7-[2-[(2-hydroxy-1-methyl-2-phenylethyl)amino]ethyl]-1,3-dimethyl-1H-purine-2,6-dione
 7-(2-((Alphas,betar)-beta-hydroxy-alpha-methylphenethylamino)ethyl)-1,3-dimethyl-2,6(1H,3H)purindion
 7-(2-{[(1R,2S)-1-Hydroxy-1-phenyl-2-propanyl]amino}ethyl)-1,3-dim ethyl-3,7-dihydro-1H-purine-2,6-dione
 1H-Purine-2,6-dione, 3,7-dihydro-7-[2-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]amino]ethyl]-1,3-dimethyl-
 |  | [Molecular Formula] 
 C18H23N5O3
 |  | [MOL File] 
 58166-83-9.mol
 |  | [Molecular Weight] 
 357.41
 | 
 | Hazard Information | Back Directory |  | [Originator] 
 Praxinor,Merck Lipha Sante
 |  | [Manufacturing Process] 
 7.5 g 7-(2-bromethyl)theophylline, 11.3 g 1-norphedrine and 12.5 ml
isopropanol were refluxed with stirring for 6 hours. Then 30 ml ethanol and
HCl in ethanol to pH 5-6 were added. The mixture stood for 2 days. 9.6 g of
7-(2-(beta-hydroxy-alpha-methylphenethylamino)ethyl)theophylline
hydrochloride was filtered off and dried. MP 243°-244°C.
 In practice it is usually used as free base.
 |  | [Therapeutic Function] 
 Analeptic
 | 
 | 
                    
                        
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