| Identification | Back Directory | [Name]
TERREIN | [CAS]
582-46-7 | [Synonyms]
TERREIN
Terrain
NSC 29130
(+)Terrein
NSC-291308
(+) Terrein, NSC 291308
(4S,5R)-4,5-Dihydroxy-3-[(E)-1-propenyl]-2-cyclopenten-1-one
(4S,5R)-4,5-Dihydroxy-3-(1E)-1-propen-1-yl-2-cyclopenten-1-one
2-Cyclopenten-1-one, 4,5-dihydroxy-3-(1E)-1-propen-1-yl-, (4S,5R)- | [Molecular Formula]
C8H10O3 | [MOL File]
582-46-7.mol | [Molecular Weight]
154.164 |
| Chemical Properties | Back Directory | [Melting point ]
125-127℃ | [Boiling point ]
327.2±42.0 °C(Predicted) | [density ]
1.449±0.06 g/cm3(Predicted) | [storage temp. ]
?20°C | [solubility ]
H2O: soluble1-1.10 mg/mL, clear, colorless | [form ]
A solid | [pka]
11.77±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
Terrein is a polar, substituted dihydrocyclopentenone first reported by Raistrick and colleagues in the 1930s and subsequently found in a number of Aspergillus and Penicillium species. For many years the biological profile and mode of action of terrein was unstudied; however, recent research showed that terrein reduces melanin synthesis by reducing tyrosinase production via ERK activation, followed by MITF down-regulation. Terrein also reduces human keratinocyte proliferation by inhibiting ERK and by decreasing the expression of cyclin B1 and Cdc2 complex. | [Definition]
ChEBI: Terrein is a polyol. |
|
| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Website: |
https://www.novachemistry.com/ |
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|