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58450-00-3

58450-00-3 Structure

58450-00-3 Structure
IdentificationBack Directory
[Name]

MS-347b
[CAS]

58450-00-3
[Synonyms]

MS-347b
Sydowinin B
2,8-Dihydroxy-6-hydroxymethyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester
9H-Xanthene-1-carboxylic acid, 2,8-dihydroxy-6-(hydroxymethyl)-9-oxo-, methyl ester
[Molecular Formula]

C16H12O7
[MOL File]

58450-00-3.mol
[Molecular Weight]

316.26
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

A solid
Hazard InformationBack Directory
[Uses]

Sydowinin B (MS-347b) is a active compound and can be isolated from A. sydowii. Sydowinin B shows has immunosuppressant activity[1][2][3].
[Definition]

ChEBI:Sydowinin B is a member of the class of xanthones that is methyl 9H-xanthene-1-carboxylate substituted by hydroxy group at positions 2 and 8, a hydroxymethyl group at position 6 and an oxo group at position 9. It has been isolated from the sea fan derived fungus Aspergillus sydowii. It has a role as an Aspergillus metabolite. It is an aromatic ester, a polyphenol and a member of xanthones.
[storage]

-20°C
[References]

[1] Chung YM, et al. An epigenetic modifier enhances the production of anti-diabetic and anti-inflammatory sesquiterpenoids from Aspergillus sydowii. Bioorg Med Chem. 2013;21(13):3866-3872. DOI:10.1016/j.bmc.2013.04.004
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