ChemicalBook--->CAS DataBase List--->58510-66-0

58510-66-0

58510-66-0 Structure

58510-66-0 Structure
IdentificationBack Directory
[Name]

Uridine, 2',5'-dideoxy-5'-iodo-
[CAS]

58510-66-0
[Synonyms]

2',5'-Dideoxy-5'-iodouridine
Uridine, 2',5'-dideoxy-5'-iodo-
[Molecular Formula]

C9H11IN2O4
[MDL Number]

MFCD28342216
[MOL File]

58510-66-0.mol
[Molecular Weight]

338.1
Chemical PropertiesBack Directory
[Melting point ]

163-164 °C(Solv: ethanol (64-17-5))
[density ]

1.987±0.06 g/cm3(Predicted)
[pka]

9.39±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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