ChemicalBook--->CAS DataBase List--->5853-29-2

5853-29-2

5853-29-2 Structure

5853-29-2 Structure
IdentificationBack Directory
[Name]

cephaeline hydrochloride
[CAS]

5853-29-2
[Synonyms]

NSC 32944
Cephaeline DiHCl
Cephaeline HCl salt
cephaelin hydrochloride
Cephaeline dihydrochloride
Cephaeline dihydrochloroide
Cephaeline hydrochloride CRS
(-)-CEPHAELINE DIHYDROCHLORIDE
(1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol hydrochloride
[EINECS(EC#)]

227-463-3
[Molecular Formula]

C28H39ClN2O4
[MDL Number]

MFCD01732155
[MOL File]

5853-29-2.mol
[Molecular Weight]

503.08
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[solubility ]

Soluble in DMSO
[form ]

neat
[color ]

White to off-white
Safety DataBack Directory
[RIDADR ]

1544
[RTECS ]

FJ9450000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[Toxicity]

LD50 oral in mouse: 74970ug/kg
Hazard InformationBack Directory
[Chemical Properties]

Off-white to yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from ipecac, Angola anise maple.
[Uses]

Epichenol hydrochloride can kill the trophozoites of lysosomes and is toxic.
[Biological Activity]

Cephaeline dihydrochloride is a selective CYP2D6 inhibitor with IC50 of 121 μM.
[target]

IC50: 121 μM (CYP2D6)
Ki: 54 μM (CYP2D6)

[IC 50]

CYP2
[storage]

4°C, protect from light
Spectrum DetailBack Directory
[Spectrum Detail]

cephaeline hydrochloride(5853-29-2)1HNMR
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