| Identification | Back Directory | [Name]
Hemslecin D | [CAS]
586960-44-3 | [Synonyms]
Hemslecin D
HemsleyadinD
Cucurbitacin IIa 16-acetate
23,24-Dihydrocucurbitacin F 16,25-diacetate
19-Norlanost-5-ene-11,22-dione, 16,25-bis(acetyloxy)-2,3,20-trihydroxy-9-methyl-, (2β,3α,9β,16α)- | [Molecular Formula]
C34H52O9 | [MOL File]
586960-44-3.mol | [Molecular Weight]
604.78 |
| Hazard Information | Back Directory | [Uses]
Hemsleyadin D is a triterpenoid compound derived from Hemsleya penxianensis with antitumor activity. Its IC50 values against K562, MGC-803, U118, HepG2, A549, and MCF-7 cells are 93.9, 47.1, 25.9, 56.1, 66.3, and 67.6 μM, respectively[1]. | [References]
[1] Li Z, et al. Cucurbitane triterpenoid entities derived from Hemsleya penxianensis triggered glioma cell apoptosis via ER stress and MAPK signalling cross-talk. Bioorg Chem. 2022 Oct;127:106013. DOI:10.1016/j.bioorg.2022.106013 |
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