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58765-21-2

58765-21-2 Structure

58765-21-2 Structure
IdentificationBack Directory
[Name]

Ciclotizolam
[CAS]

58765-21-2
[Synonyms]

We-973BS
Ciclotizolam
2-Bromo-4-(o-chlorophenyl)-9-cyclohexyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine, 2-bromo-4-(2-chlorophenyl)-9-cyclohexyl-
[Molecular Formula]

C20H18BrClN4S
[MDL Number]

MFCD00868172
[MOL File]

58765-21-2.mol
[Molecular Weight]

461.81
Chemical PropertiesBack Directory
[solubility ]

DMF: 2 mg/ml
DMSO: 5 mg/ml
Ethanol: 10 mg/ml
Hazard InformationBack Directory
[Uses]

Ciclotizolam (WE-973) is a thienotriazolodiazepine with anticonvulsant and anti-aggressive activities. Ciclotizolam binds to benzodiazepine receptors in the central nervous system. Ciclotizolam decreases total sleep time in cats[1].
[References]

[1] Weber KH, et al. Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines'). Eur J Pharmacol. 1985 Feb 12;109(1):19-31. DOI:10.1016/0014-2999(85)90535-7
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