| Identification | Back Directory | [Name]
INGENOL 3,20-DIBENZOATE | [CAS]
59086-90-7 | [Synonyms]
ingenoldibenzoate
INGENOL 3,20-DIBENZOATE
1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 6-(benzoyloxy)-4-[(benzoyloxy)methyl]-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)- | [Molecular Formula]
C34H36O7 | [MDL Number]
MFCD00211027 | [MOL File]
59086-90-7.mol | [Molecular Weight]
556.65 |
| Chemical Properties | Back Directory | [Melting point ]
>95°C (dec.) | [storage temp. ]
−20°C
| [solubility ]
Acetontrile (Slightly), Chloroform (Slightly) | [form ]
Colorless oil. | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Ingenol 3,20-dibenzoate is an activator of protein kinase C (PKC) and apoptotic inducer. | [in vivo]
Ingenol 3,20-dibenzoate (20 μg/mouse; i.p.; on days 3, 7, and 11) lessens the anemia induced by 5-fluorouracil in an in vivo mouse model[3]. | Animal Model: | Male C57BL/6 mice (8–12 weeks old)[3] | | Dosage: | 20 μg/mouse | | Administration: | I.p.; On days 3, 7, and 11 | | Result: | Severity of 5-FU–induced anemia was lessened by IDB treatment on days 12 and 20.
|
| [storage]
Store at -20°C |
|
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
|