| Identification | Back Directory | [Name]
4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester | [CAS]
5948-71-0 | [Synonyms]
Ethyl 4-(4-chlorophenyl)
-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
ethyl 4-(4-chlorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
Ethyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-Pyrimidinecarboxylic acid ethyl ester
4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester
5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, ethyl ester | [Molecular Formula]
C14H15ClN2O3 | [MDL Number]
MFCD00183936 | [MOL File]
5948-71-0.mol | [Molecular Weight]
294.73 |
| Chemical Properties | Back Directory | [Melting point ]
213-215 °C | [Boiling point ]
411.8±45.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
11.16±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in Laboratory research and development process and chemical production process. | [Synthesis]
Substituted benzaldehyde (6.617×10-3mmol; 1.0 equiv.) is mixed with slightly excess equivalent of urea (6.749×10-3mmol; 1.02 equiv.) and ethyl acetoacetate (6.749×10-3mmol; 1.02 equiv.) in the presence of catalytic concentration 1.0×10-4mmol of our synthesized dimeric pyridinium salts along with dry MeCN at ambient reaction condition from 6-33 min. reaction condition. Yield: 92% | [References]
[1] Journal of the Iranian Chemical Society, 2017, vol. 14, # 1, p. 75 - 87
[2] Phosphorus, Sulfur and Silicon and the Related Elements, 2010, vol. 185, # 2, p. 325 - 329
[3] Heteroatom Chemistry, 2007, vol. 18, # 6, p. 684 - 687 |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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