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5948-71-0

5948-71-0 Structure

5948-71-0 Structure
IdentificationBack Directory
[Name]

4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester
[CAS]

5948-71-0
[Synonyms]

Ethyl 4-(4-chlorophenyl)
-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
ethyl 4-(4-chlorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
Ethyl 4-(4-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-Pyrimidinecarboxylic acid ethyl ester
4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester
5-Pyrimidinecarboxylic acid, 4-(4-chlorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-, ethyl ester
[Molecular Formula]

C14H15ClN2O3
[MDL Number]

MFCD00183936
[MOL File]

5948-71-0.mol
[Molecular Weight]

294.73
Chemical PropertiesBack Directory
[Melting point ]

213-215 °C
[Boiling point ]

411.8±45.0 °C(Predicted)
[density ]

1.256±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

11.16±0.70(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS02
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H226
[Precautionary statements ]

P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
Hazard InformationBack Directory
[Uses]

4-(4-Chloro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid ethyl ester can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in Laboratory research and development process and chemical production process.
[Synthesis]

3.jpg
Substituted benzaldehyde (6.617×10-3mmol; 1.0 equiv.) is mixed with slightly excess equivalent of urea (6.749×10-3mmol; 1.02 equiv.) and ethyl acetoacetate (6.749×10-3mmol; 1.02 equiv.) in the presence of catalytic concentration 1.0×10-4mmol of our synthesized dimeric pyridinium salts along with dry MeCN at ambient reaction condition from 6-33 min. reaction condition. Yield: 92%
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