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59527-84-3

59527-84-3 Structure

59527-84-3 Structure
IdentificationBack Directory
[Name]

β-D-Glucopyranosiduronic acid, (3β,16α)-13,28-epoxy-16-hydroxyoleanan-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→2)]-
[CAS]

59527-84-3
[Synonyms]

β-D-Glucopyranosiduronic acid, (3β,16α)-13,28-epoxy-16-hydroxyoleanan-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→2)]-
[Molecular Formula]

C60H98O27
[MOL File]

59527-84-3.mol
[Molecular Weight]

1251.4
Chemical PropertiesBack Directory
[density ]

1.50±0.1 g/cm3(Predicted)
[pka]

2.68±0.70(Predicted)
Hazard InformationBack Directory
[Description]

Sakurasosaponin is a compound isolated from the plant J. flammea and has been identified to have antifungal effects.
[Uses]

Sakurasosaponin is a saponin with potential anticancer activity that can be extracted from the root of Primula sieboldii. Sakurasosaponin can activate the AMPK pathway to induce cell autophagy and exert anti-NSCLC cell proliferation activity. Sakurasosaponin also has antifungal activity and significantly inhibits the growth of anthrax.
[References]

[1] Seo Y, Lim C, Lee J, Kim J, Kim YH, Lee PCW, Jang SW. Sakurasosaponin inhibits lung cancer cell proliferation by inducing autophagy via AMPK activation. Oncol Lett. 2023 Oct 5;26(6):501. DOI:10.3892/ol.2023.14088
[2] García-Sosa K, et al. Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea. Nat Prod Res. 2011 Jul;25(12):1185-9. DOI:10.1080/14786419.2010.511215
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