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59708-49-5

59708-49-5 Structure

59708-49-5 Structure
IdentificationBack Directory
[Name]

2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-(1-phenylethyl)-4-piperidinyl]-
[CAS]

59708-49-5
[Synonyms]

2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-(1-phenylethyl)-4-piperidinyl]-
[Molecular Formula]

C20H23N3O
[MOL File]

59708-49-5.mol
[Molecular Weight]

321.42
Chemical PropertiesBack Directory
[density ]

1.195±0.06 g/cm3(Predicted)
[solubility ]

DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: insol; PBS (pH 7.2): insol
[form ]

A crystalline solid
[pka]

12.04±0.30(Predicted)
Hazard InformationBack Directory
[Description]

Orphine is an analytical reference standard categorized as an opioid.1 This product is intended for research and forensic applications.
[Uses]

Orphine is an opioid compound. Orphine can enhance the antinociceptive effects in mice that are mitigated by Naloxone (HY-17417)[1][2].
[References]

1. Kennedy, N.M., Schmid, C.L., Ross, N.C., et al. Optimization of a series of mu opioid receptor (MOR) agonists with high G protein signaling bias J. Med. Chem. 61(19),8895-8907(2018).
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