| Identification | Back Directory | [Name]
N-DESMETHYL ZOPICLONE | [CAS]
59878-63-6 | [Synonyms]
Norzopiclone
Desmethylzopiclone
N-DESMETHYL ZOPICLONE
N-Desmethyl Zopiclone HCl
N-Desmethyl Zopiclone Hydrochloride
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxyl
6-(5-CHLOROPYRIDIN-2-YL)-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRAZIN-5-YL PIPERAZINE-1-CARBOXYLATE
1-Piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b] pyrazin-5-yl ester
Piperazine -1-carboxylic Acid 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5yl Ester Hydrochloride | [Molecular Formula]
C16H16Cl2N6O3 | [MDL Number]
MFCD08063745 | [MOL File]
59878-63-6.mol | [Molecular Weight]
411.24 |
| Chemical Properties | Back Directory | [Appearance]
White to Off-White Solid | [Melting point ]
226-2280C | [Boiling point ]
599.0±50.0 °C(Predicted) | [density ]
1.57±0.1 g/cm3(Predicted) | [Fp ]
2°C | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
8.26±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
A metabolite of Zopiclone (Z700500). | [in vivo]
A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive[2]. N-oxide-Zopiclone has a similar t1/2 compared to parent Zopiclone, while the t1/2 of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h[3]. |
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