| Identification | Back Directory | [Name]
(4R,6R,7E,10Z)-2,3,3aβ,4,5,6,9,11aα-Octahydro-3-methylene-6-hydroxy-2,9-dioxo-4-(2-methylpropanoyloxy)-6,10-dimethylcyclodeca[b]furan | [CAS]
59979-56-5 | [Synonyms]
Tagitinin C
(4R,6R,7E,10Z)-2,3,3aβ,4,5,6,9,11aα-Octahydro-3-methylene-6-hydroxy-2,9-dioxo-4-(2-methylpropanoyloxy)-6,10-dimethylcyclodeca[b]furan
2-Methylpropanoic acid (3aR,4R,6R,7E,10Z,11aR)-2,3,3a,4,5,6,9,11a-octahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,9-dioxocyclodeca[b]furan-4-yl ester | [MOL File]
59979-56-5.mol |
| Hazard Information | Back Directory | [Description]
Tagitinim C is an antitrypanosomal compound from the moon flower, Tithonia diversifolia. | [Uses]
Tagitinin C is a sesquiterpenoid compound isolated from the Tithonia diversifolia. Tagitinin C has anticancer activity and can inhibit the proliferation of human glioblastoma U373 cells with an IC50 of 6.1 μg/mL. Tagitinin C can induce U373 cell death and be used in glioblastoma research[1]. | [References]
[1] Lee MY,et al. Identification and anti-human glioblastoma activity of tagitinin C from Tithonia diversifolia methanolic extract. J Agric Food Chem. 2011 Mar 23;59(6):2347-55. DOI:10.1021/jf105003n |
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