| Identification | Back Directory | [Name]
GUANETHIDINE HEMISULFATE | [CAS]
60-02-6 | [Synonyms]
Iporal
octadin
su-5864
Oktadin
Guethine
octadine
isobarin
nsc-29863
octatensin
Oktatenzin
Sanotensin
ISMELIN SULFATE
guanetidinsulfate
Octatensin sulfate
GUANETHIDINE SULFATE
guanethidinebisulfate
guanethidine sulphate
Guanethidine hemisulfate
GUANETHIDINEHEMISULPHATE
.Beta.-1-Azacyclooctylethylguanidine
beta-1-azacyclooctylethylguanidinesulfate
2-(1'-Azacyclooctyl)ethylguanidinesulfate
1-(2-(azocan-1-yl)ethyl)guanidine hemisulfate
2-(1'-AZACYCLOOCTYL)ETHYLGUANIDINE HEMISULFATE
(2-(octahydro-1-azocinyl)ethyl)guanidinesulfate
1-(2-guanidinoethyl)octahydro-azocinsulfate(2:1)
2-(1-N,N-Heptamethyleneimino)ethylguanidinesulfate
(2-(hexahydro-1(2h)-azocinyl)ethyl)guanidinesulfate
(2-(hexahydro-1(2h)-azocinyl)ethyl)-guanidinsulfate
(2-(octahydro-1-azocinyl)ethyl)-guanidinsulfate(2:1)
N-[2-(Hexahydro-1(2H)-azocinyl)ethyl]guanidine Sulfate
2-(1-N,N-HEPTAMETHYLENEIMINO)ETHYLGUANIDINE HEMISULFATE
(2-(hexahydro-1(2h)-azocinyl)ethyl)-guanidinsulfate(2:1)
Guanidine, 2-(hexahydro-1(2H)-azocinyl)ethyl-, sulfate (2:1)
Guanidine, N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-, sulfate (2:1) | [EINECS(EC#)]
200-452-0 | [Molecular Formula]
C20H46N8O4S | [MDL Number]
MFCD00079332 | [MOL File]
60-02-6.mol | [Molecular Weight]
494.7 |
| Chemical Properties | Back Directory | [Melting point ]
255-265°C | [density ]
1.1052 (rough estimate) | [refractive index ]
1.7400 (estimate) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White | [Merck ]
4560 | [Stability:]
Hygroscopic | [CAS DataBase Reference]
60-02-6 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Originator]
Ismelin,Ciba,US,1960 | [Uses]
Antihypertensive; antiglaucoma | [Definition]
ChEBI: A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid. | [Manufacturing Process]
13.6 grams of chloroacetyl guanide is added while stirring to a solution of
22.6 grams of heptamethylene imine in 200 ml of benzene. After warming for
1 hour, and then cooling, the solution is filtered and the filtrate concentrated
under reduced pressure. The residue, containing the 2-(1-N,N-heptamethylene-imino)-aceticacid guanide, is suspended in tetrahydrofuran
and added to a refluxing solution of 6 grams of lithium aluminum hydride in
tetrahydrofuran. After completion of the reaction, the excess of lithium
aluminum hydride is decomposed by adding water, then aqueous sodium
hydroxide. The solid material is filtered off, the filtrate is acidified with sulfuric
acid and the 2-(1-N,N-heptamethylene-imino)-ethyl-guanidine sulfate can be
recovered and recrystallized from aqueous ethanol, MP 276° to 281°C (with
decomposition). | [Therapeutic Function]
Antihypertensive |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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