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60111-76-4

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60111-76-4 Structure

60111-76-4 Structure
IdentificationBack Directory
[Name]

BOC-D-LEU-OSU
[CAS]

60111-76-4
[Synonyms]

BOC-D-LEU-OSU
BOC-D-LEUCINE-OSU
(Tert-Butoxy)Carbonyl D-Leu-Osu
BOC-D-LEUCINE N-HYDROXYSUCCINIMIDE ESTER
Boc-D-leucineN-hydroxysuccinimide ester99%
(R)-Boc-2-amino-4-methyl-pentanoic acid N-hydoxysuccinimide ester
D-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester
(R)-2,5-Dioxopyrrolidin-1-yl 2-((tert-butoxycarbonyl)amino)-4-methylpentanoate
2,5-dioxopyrrolidin-1-yl (2R)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanoate
[Molecular Formula]

C15H24N2O6
[MDL Number]

MFCD00236854
[MOL File]

60111-76-4.mol
[Molecular Weight]

328.36
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[solubility ]

DMF: 30 mg/ml; Ethanol: 30 mg/ml
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

Boc-D-Leu-OSu is an amino acid-containing building block. It has been used in the synthesis of peptide gastrin antagonists, as well as analogs of the peptide antibiotic gramicidin S.
[Uses]

Boc-D-Leu-OSu is an amino acids building block. Boc-D-Leu-OSu can be used to synthesize analogues of gastrin antagonist and antibiotic Gramicidin S[1][2].
[storage]

Store at -20°C
[References]

[1] Rodriguez M, et al. Synthesis of gastrin antagonists, analogues of the C-terminal tetrapeptide of gastrin, by introduction of a beta-homo residue. J Med Chem. 1989 Mar;32(3):522-8. DOI:10.1021/jm00123a003
[2] Sato, et al. Design and Synthesis of Gramicidin S Analogs with High Antibiotic Activity.Bulletin of the Chemical Society of Japan, 2013, 86(1):112-120.
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