ChemicalBook--->CAS DataBase List--->60133-18-8

60133-18-8

60133-18-8 Structure

60133-18-8 Structure
IdentificationBack Directory
[Name]

1(ALPHA) 25-DIHYDROXYVITAMIN D2*
[CAS]

60133-18-8
[Synonyms]

1-alpha
H,5&alpha
Ro 17-6218
Ercalcitriol
-Hydroxy Vitamin D2
-Methylandrosterone
H-guaia-6-ene-4&beta
-Methyl Dapagliflozin
-Hydroxy Vitamin D2-d3
25-dihydroxy VitaMin D2
1α,25-dihydroxycalciferol
1α,25-dihydroxyvitamin d2
1α,25-dihydoxyergocalciferol
1a,25-dihydoxyergocalciferol
1alpha,25-Dihydroxycalciferol
1alpha,25-Dihydroxyvitamin D2
1α,25-Dihydroxyvitamin D2, >=98%
(1S,3S,Z)-5-((E)-2-((1R,3aS,7aR)-1
1α,25-Dihydroxyvitamin D2 solution
1-alpha, 25-Dihydroxy Vitamin D2-d6
1A,25-DIHYDROXYVITAMIN D2 >= 97.0% (
1α,25-DihydroxyvitaMin D2
1alpha,25-Dihydroxyvitamin D2 solution
Ercalcitriol(1a,25-DihydroxyvitaMin D2)
-D-Arabinofuranosyl-2-nitro-1H-imidazole
1α,25-DihydroxyVitaminD2-[d6](98%,99Atom%D)
-Chloromethyl-3,6,20-pregn-4-en-17-yl Acetate
Doxercalciferol Impurity 2(25-Hydroxy Doxercalciferol)
(1α,3β,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraene-1,3,25-triol
(1R,3S,5Z)-4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4
(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7α-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-triMethyl-2-hexen-1-yl]-7a-Methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol
1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-
[EINECS(EC#)]

634-659-6
[Molecular Formula]

C28H44O3
[MDL Number]

MFCD00869499
[MOL File]

60133-18-8.mol
[Molecular Weight]

428.65
Chemical PropertiesBack Directory
[Boiling point ]

577.7±50.0 °C(Predicted)
[density ]

1.06±0.1 g/cm3(Predicted)
[Fp ]

14℃
[storage temp. ]

-20°C
[solubility ]

Ethanol: 1 mg/ml
[form ]

Powder
[pka]

14.43±0.40(Predicted)
[color ]

White to off-white
[biological source]

synthetic
[BRN ]

5635017
[Stability:]

Light sensitive, Temperature sensitive
[InChIKey]

ZGLHBRQAEXKACO-KYHOFSCESA-N
[SMILES]

[C@@H]1(O)C/C(=C/C=C2\CCC[C@@]3(C)[C@@]\2([H])CC[C@@H]3[C@H](C)/C=C/C(C)C(O)(C)C)/C(=C)[C@@H](O)C1
Safety DataBack Directory
[Hazard Codes ]

T,T+,F
[Risk Statements ]

23/24/25-63-48/25-26-24/25-11
[Safety Statements ]

36/37-45-28-16-7
[RIDADR ]

UN 2811 6.1/PG 2
[WGK Germany ]

3
[F ]

8-10-19
[Storage Class]

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
[Hazard Classifications]

Acute Tox. 2 Inhalation
Acute Tox. 3 Dermal
Acute Tox. 3 Oral
STOT RE 1 Oral
Hazard InformationBack Directory
[Uses]

The active metabolite of Vitamin D2 (V676040).
[Definition]

ChEBI: A hydroxycalciol that is vitamin D2 bearing additional hydroxy substituents at positions 1alpha and 25.
[General Description]

1α,25-Dihydroxyvitamin D2?is an active form of vitamin D2. It is also known as ercalcitriol or 1α,25-dihydroxyergocalciferol. It was first isolated from mitochondria of chick kidney.
[Biochem/physiol Actions]

Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.
[IC 50]

Human Endogenous Metabolite
[storage]

Store at -20°C,unstable in solution, ready to use.
Spectrum DetailBack Directory
[Spectrum Detail]

1(ALPHA) 25-DIHYDROXYVITAMIN D2*(60133-18-8)1HNMR
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