| Identification | Back Directory | [Name]
ETACONAZOLE | [CAS]
60207-93-4 | [Synonyms]
benit
sonax
C11293
vangard
cga64251
ETACONAZOL
ETACONAZOLE
Etaconazole 0
Picoxystrobin Impurity 9
Etaconazole Solution, 100ppm
Etaconazole Solution, 1000ppm
Etaconazole @100 μg/mL in Methanol
Etaconazole@1000 μg/mL in Methanol
1-((2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl)methyl)-
(+/-)-1-[2-(2,4-DICHLOROPHENYL)-4-ETHYL-1,3-DIOXOLAN-2-YL]-1H-1,2,4-TRIAZOLE
1-((2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl)methyl)-1h-1,2,4-triazo
4-triazole,1-((2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl)methyl)-1h-2
1h-1,2,4-triazole,1-((2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl)methyl)
1-[[2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole | [EINECS(EC#)]
262-107-0 | [Molecular Formula]
C14H15Cl2N3O2 | [MDL Number]
MFCD00078700 | [MOL File]
60207-93-4.mol | [Molecular Weight]
328.19 |
| Chemical Properties | Back Directory | [Melting point ]
75-93℃ | [Boiling point ]
470.2±55.0 °C(Predicted) | [density ]
1.5146 (rough estimate) | [refractive index ]
1.6070 (estimate) | [storage temp. ]
-20°C | [pka]
2.94±0.12(Predicted) | [Henry's Law Constant]
7.9×103 mol/(m3Pa) at 25℃, MacBean (2012) | [Major Application]
agriculture
environmental | [InChI]
1S/C14H15Cl2N3O2/c1-2-11-6-20-14(21-11,7-19-9-17-8-18-19)12-4-3-10(15)5-13(12)16/h3-5,8-9,11H,2,6-7H2,1H3 | [InChIKey]
DWRKFAJEBUWTQM-UHFFFAOYSA-N | [SMILES]
CCC1COC(Cn2cncn2)(O1)c3ccc(Cl)cc3Cl | [EPA Substance Registry System]
Etaconazole (60207-93-4) |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [HS Code ]
29349990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless crystals. Melting point 75-93°C. Its nitrate salt has a melting point of 122°C. Solubility (g/kg) at 20°C: acetone 300, dichloromethane 700, methanol 400, isopropanol 100, toluene 250, water 0.08. | [Uses]
Etaconazol is a pesticide and fungicide. | [Definition]
ChEBI: A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2,4-dichlorophenyl and 1,2,4-triazol-1-ylmethyl groups and at position 4 by an ethyl group. An obsolete fungicide that was used to control powdery mildew on fruit and ot
er crops. | [Production Methods]
Etaconazole is commercially synthesised through a multi-step process involving the formation of a triazole-based fungicidal compound. The key reaction involves the condensation of a 1,2,4-triazole ring with a substituted dioxolane moiety, specifically 2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-ylmethyl. This intermediate is then linked to the triazole via a meth ylene bridge, forming the final active molecule: 1-[[2-(2,4-dichlorophenyl)-4-ethyl-1,3-dioxolan-2-yl]methyl]-1H-1,2,4-triazole. The synthesis requires precise control of stereochemistry, as etaconazole is a chiral compound with multiple isomers, and the 2S,4R-isomer exhibits the highest fungicidal activity. | [Mechanism of action]
Sterol biosynthesis inhibition | [Pesticide Type]
Fungicide |
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