| Identification | Back Directory | [Name]
3,6-diamino-10-methylacridinium chloride monohydrochloride | [CAS]
6034-59-9 | [Synonyms]
Nsc163949
3,6-diamino-10-methylacridinium chloride monohydrochloride
Acridinium, 3,6-diamino-10-methyl-, chloride, monohydrochloride | [EINECS(EC#)]
227-911-8 | [Molecular Formula]
C14H15Cl2N3 | [MOL File]
6034-59-9.mol | [Molecular Weight]
296.195 |
| Hazard Information | Back Directory | [Originator]
Acriflavine
hydrochloride,ABCR GmbH and Co. KG | [Manufacturing Process]
4,4-Diaminodiphenylmethane reacted with HNO3 and as a result of this
reaction 4,4-diamino-2,2-dinitro-diphenylmethane was obtained.
By reducing of 4,4-diamino-2,2-dinitro-diphenylmethane with HCl and Sn,
2,2,4,4-tetraaminodiphenylmethane was produced, which at heating to 150°C
gave 3,6-diamino-9,10-dihydroacridine.
The 3,6-diamino-9,10-dihydroacridine by oxidation with FeCl3 was converted
to 3,6-diaminoacridine.
3,6-Diaminoacridine was reacted with acetanhydride and 3,6-bis-
(acetylamino)-acridine was produced.
3,6-Bis-(acetylamino)-acridine was methylated by p-toluolsulfomethyl ether
and 3,6-bis-(acetylamino)-10-methylacridinumtosylate was produced.
Then the 3,6-bis-(acetylamino)-10-methylacridinumtosylate was converted to
3,6-diamino-10-methylacridinum chloride (acriflavinum chloride) by reaction
with hydrochloric acid. | [Therapeutic Function]
Antiseptic, Topical antibacterial |
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