| Identification | Back Directory | [Name]
EpicoccaMide | [CAS]
606139-26-8 | [Synonyms]
EpicoccaMide
Epicoccamide A
3H-Pyrrol-3-one, 1,2-dihydro-5-hydroxy-4-[16-(β-D-mannopyranosyloxy)-2-methyl-1-oxohexadecyl]-1,2-dimethyl- | [Molecular Formula]
C29H51NO9 | [MDL Number]
MFCD33021228 | [MOL File]
606139-26-8.mol | [Molecular Weight]
557.72 |
| Hazard Information | Back Directory | [Description]
Epicoccamide is a marine fungal metabolite originally isolated from E. purpurascens. It is comprised of three subunits including a glycosidic subunit, a fatty acid, and a tetramic acid. Epicoccamide has no activity against various bacteria, fungi, and nematodes and is not cytotoxic. | [Uses]
Epicoccamide is an ornate linear fatty acid with an acyl tetronic acid terminus and glycosidic alkyl terminus. Secondary metabolites of Epicoccum nigrum showed cytotoxic, anticancer, antimicrobial and anti-diabetic activities indicating Epicoccum nigrum is emerging source of unique bioactive metabolites. It is useful in biological studies. | [IC 50]
Microbial Metabolite | [References]
[1] ANTHONY D. WRIGHT Gabriele M K Claudia Osterhage. Epicoccamide, a Novel Secondary Metabolite from a Jellyfish-Derived Culture of Epicoccum purpurascens.[J]. ChemInform, 2003, 34 26. DOI: 10.1002/chin.200326229
[2] HILAIRE V. KEMAMI WANGUN Christian H Hans Martin Dahse. Epicoccamides B–D, Glycosylated Tetramic Acid Derivatives from an Epicoccum sp. Associated with the Tree Fungus Pholiota squarrosa[J]. Journal of Natural Products , 2007, 70 11: 1800-1803. DOI: 10.1021/np070245q |
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