| Identification | Back Directory | [Name]
Elcatonin | [CAS]
60731-46-6 | [Synonyms]
hc-58
ELCATONIN
29-l-alanine-
ELCATONIN (EEL)
CARBOCALCITONIN
Elcatonin Acetate
ELCATONIN, 98.0+%
CARBACALCITONIN (EEL)
(ASU1'7)-CALCITONIN (EEL)
[ASU1,7]-CALCITONIN (EEL)
(aminosubericacid1,7)-eelcalcitonin
Elcatonin, (Asu1·7)-Calcitonin (eel)
(ASU1,7)-CALCITONIN (EEL) ACETATE SALT
1,7-DICARBACALCITONIN, 1-BUTANOIC ACID-
(L-ALPHA-AMINOSUBERIC ACID1,7)-CALCITONIN (EEL)
(DES CYS1,CYCLO (SER2-ASU7))-CALCITONIN (EEL) ACETATE SALT
1-butanoicacid-26-l-asparticacid-27-l-valine-7-dicarbacalcitonin(salmon)
Des-Cys1,cyclo(Ser2-Asu7))-Calcitonin (eel), Elcatonin, (Asu17)-Calcitonin (eel)
Cyclo(-Ser-Asn-Leu-Ser-Thr-Asu)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2
CYCLO(-SER-ASN-LEU-SER-THR-ASU)-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO-NH2
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Thr-Pro-NH2 cyclic (1-6)
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro (Ser----Asu)
Cyclo(-Ser-Asn-Leu-Ser-Thr-Asu)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 acetate salt | [EINECS(EC#)]
262-393-7 | [Molecular Formula]
C148H244N42O47 | [MDL Number]
MFCD00221767 | [MOL File]
60731-46-6.mol | [Molecular Weight]
3363.77 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [RTECS ]
HS9270000 | [storage temp. ]
-15°C
| [Sequence]
H-Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-OH?(Ser-Asu Lacton) | [InChIKey]
DDPFHDCZUJFNAT-KDIBENGQNA-N |
| Hazard Information | Back Directory | [Uses]
Osteoporosis; Hypercalcemia; Paget’s disease | [Hazard]
A poison by ingestion. | [in vivo]
Elcatonin (Carbocalcitonin) (20 U/kg; s.c.; 2 d after oxaliplatin administration) attenuats oxaliplatin-induced cold and mechanical allodynia in rats[2]. | Animal Model: | Male Sprague-Dawley rats weighing 150-250 g (Oxaliplatin-Induced Allodynia Models)[1] | | Dosage: | 20 U/kg | | Administration: | Subcutaneously; 2 d after oxaliplatin administration | | Result: | Attenuated oxaliplatin-induced cold in rtas. |
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| Questions And Answer | Back Directory | [Description]
Elcatonin (molecular formula: C148H244N42O47) is a kind of single, non-glycosylated polypeptide chain consisting of 31 amino acids. It is a calcitonin derivative, and is used as an anti-parathyroid agent. It is mainly used for remitting and eliminating the pain induced by Osteoporosis. It has several physiological effects including: (1) inhibit the absorption and autolysis of bones, thus leading to the reduction of the blood calcium level; (2) inhibit the dissolving and transferring of bone salts, further promoting the excretion of calcium and phosphorus in urine; (3) it inhibits the process of calcium, phosphorus and sodium re-absorption by renal tubules.
| [References]
http://www.prospecbio.com/Elcatonin_7_42/
https://en.wikipedia.org/wiki/Elcatonin
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| Company Name: |
Phygene Gold
|
| Telephone: |
18059081430 |
| Website: |
www.phygene.com/ |
| Company Name: |
Jinan Putubio Tech Co., Ltd.
|
| Telephone: |
+86 (531) 8099-2215 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList16923/0_EN.htm |
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