ChemicalBook--->CAS DataBase List--->60731-46-6

60731-46-6

60731-46-6 Structure

60731-46-6 Structure
IdentificationBack Directory
[Name]

Elcatonin
[CAS]

60731-46-6
[Synonyms]

hc-58
ELCATONIN
29-l-alanine-
ELCATONIN (EEL)
CARBOCALCITONIN
Elcatonin Acetate
ELCATONIN, 98.0+%
CARBACALCITONIN (EEL)
(ASU1'7)-CALCITONIN (EEL)
[ASU1,7]-CALCITONIN (EEL)
(aminosubericacid1,7)-eelcalcitonin
Elcatonin, (Asu1·7)-Calcitonin (eel)
(ASU1,7)-CALCITONIN (EEL) ACETATE SALT
1,7-DICARBACALCITONIN, 1-BUTANOIC ACID-
(L-ALPHA-AMINOSUBERIC ACID1,7)-CALCITONIN (EEL)
(DES CYS1,CYCLO (SER2-ASU7))-CALCITONIN (EEL) ACETATE SALT
1-butanoicacid-26-l-asparticacid-27-l-valine-7-dicarbacalcitonin(salmon)
Des-Cys1,cyclo(Ser2-Asu7))-Calcitonin (eel), Elcatonin, (Asu17)-Calcitonin (eel)
Cyclo(-Ser-Asn-Leu-Ser-Thr-Asu)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2
CYCLO(-SER-ASN-LEU-SER-THR-ASU)-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO-NH2
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Thr-Pro-NH2 cyclic (1-6)
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro (Ser----Asu)
Cyclo(-Ser-Asn-Leu-Ser-Thr-Asu)-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 acetate salt
[EINECS(EC#)]

262-393-7
[Molecular Formula]

C148H244N42O47
[MDL Number]

MFCD00221767
[MOL File]

60731-46-6.mol
[Molecular Weight]

3363.77
Chemical PropertiesBack Directory
[density ]

1.49±0.1 g/cm3(Predicted)
[RTECS ]

HS9270000
[storage temp. ]

-15°C
[Sequence]

H-Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-OH?(Ser-Asu Lacton)
Hazard InformationBack Directory
[Uses]

Osteoporosis; Hypercalcemia; Paget’s disease
[Hazard]

A poison by ingestion.
Safety DataBack Directory
[Safety Profile]

experimental neoplastigenic data by skin
Questions And AnswerBack Directory
[Description]

Elcatonin (molecular formula: C148H244N42O47) is a kind of single, non-glycosylated polypeptide chain consisting of 31 amino acids. It is a calcitonin derivative, and is used as an anti-parathyroid agent. It is mainly used for remitting and eliminating the pain induced by Osteoporosis. It has several physiological effects including: (1) inhibit the absorption and autolysis of bones, thus leading to the reduction of the blood calcium level; (2) inhibit the dissolving and transferring of bone salts, further promoting the excretion of calcium and phosphorus in urine; (3) it inhibits the process of calcium, phosphorus and sodium re-absorption by renal tubules.
[References]

http://www.prospecbio.com/Elcatonin_7_42/
https://en.wikipedia.org/wiki/Elcatonin
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