ChemicalBook--->CAS DataBase List--->61-00-7

61-00-7

61-00-7 Structure

61-00-7 Structure
IdentificationBack Directory
[Name]

acepromazine
[CAS]

61-00-7
[Synonyms]

1522CB
A 23051
Notensil
Aids013600
Vetranquil
Aids-013600
acepromazine
Acetylperazine
Acetopromazine
Acetylpromazine
3598-37-6 (Maleate)
acepromazine USP/EP/BP
Acetopromazine maleate salt
Acepromazine DISCONTINUED, offer A130900
Acepromazine (base and/or unspecified salts)
10-(3-DIMETHYLAMINOPROPYL)PHENOTHIAZINE-3-ETHYLONE
1-[10-(3-dimethylaminopropyl)phenothiazin-2-yl]ethanone
KETONE,10-(3-(DIMETHYLAMINO)PROPYL)PHENOTHIAZIN-2-YLMETHYL
Ethanone, 1-10-3-(dimethylamino)propyl-10H-phenothiazin-2-yl-
10-[3-[Dimethylamino] propyl] phenothiazin-2-yl methyl ketone
[EINECS(EC#)]

200-496-0
[Molecular Formula]

C19H22N2OS
[MDL Number]

MFCD00867988
[MOL File]

61-00-7.mol
[Molecular Weight]

326.456
Chemical PropertiesBack Directory
[Melting point ]

<25 °C
[Boiling point ]

bp0.5 220-240°
[density ]

1.1075 (rough estimate)
[refractive index ]

1.5950 (estimate)
[pka]

9.41±0.28(Predicted)
[color ]

Orange oil
[Water Solubility ]

16mg/L(25 ºC)
Hazard InformationBack Directory
[Uses]

Sedative (veterinary).
[Chemical Properties]

Orange-yellow oily liquid. Boiling point 220-240°C (66.5 Pa). Its maleate salt is yellow crystals with a melting point of 135-136°C. It is soluble in water; a 0.1% aqueous solution has a pH of 5.2. It is odorless and tastes bitter.
[Definition]

ChEBI: Acepromazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10. It has a role as a phenothiazine antipsychotic drug. It is a methyl ketone, an aromatic ketone, a tertiary amino compound and a member of phenothiazines.
[in vivo]

Acepromazine (25 mg/kg; systemic injection) prevents the mortality and virtually eliminated the cardiac instability[3].

Safety DataBack Directory
[Safety Profile]

Poison by ingestion, intravenous, and subcutaneous routes. A flammable liquid. When heated to decomposition it emits toxic fumes of SO, and NOx,. See also KETONES. An animal tranquilizer.
[Toxicity]

LD50 intraperitoneal in mouse: 350mg/kg
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