ChemicalBook--->CAS DataBase List--->610318-03-1

610318-03-1

610318-03-1 Structure

610318-03-1 Structure
IdentificationBack Directory
[Name]

RGX-104 HCl
[CAS]

610318-03-1
[Synonyms]

CPD1632
RGX-104
CS-2843
RGX-104 (HCl)
RGX-104 hydrochloride
RGX 104;RGX104;CPD1632
RGX-104;RGX 104;RGX104
2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid
[Molecular Formula]

C34H34Cl2F3NO3
[MDL Number]

MFCD31657403
[MOL File]

610318-03-1.mol
[Molecular Weight]

632.54
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : ≥ 130 mg/mL (218.09 mM);Water : < 0.1 mg/mL (insoluble)
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

RGX-104 is pharmaceutical formulations with improved stability.Liver X receptor beta agonist.
[in vivo]

Oral administration of GW3965 or RGX-104 hydrochloride to animals bearing palpable tumors significantly suppresses the growth of multiple cancer types. Strong tumor growth suppression is also observed in animals bearing large tumors. In some instances, the treatment causes partial or complete tumor regression. Responses are seen across a wide spectrum of malignancies, including lung cancer, melanoma, glioblastoma, and ovarian, renal cell, triple-negative breast, and colon cancer[1].

[storage]

4°C, protect from light
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