| Identification | Back Directory | [Name]
ZIMELIDINE 2HCL | [CAS]
61129-30-4 | [Synonyms]
ZIMELIDINE 2HCL
Zimeldine hydrochloride hydrate
ZIMELIDINE DIHYDROCHLORIDE SEROTONIN UPT AKE INHI
3-(4-Bromophenyl)-N,N-dimethyl-3-(3-pyridinyl)-2-propen-1-amine dihydrochloride
(z)-3-(4-bromophenyl)-n,n-dimethyl-3-(3-pyridinyl)-2-propen-1-amine dihydrobromide | [Molecular Formula]
Br1C16H17N2 | [MDL Number]
MFCD00069358 | [MOL File]
61129-30-4.mol | [Molecular Weight]
390.15 |
| Chemical Properties | Back Directory | [Melting point ]
193° | [solubility ]
0.1 M HCl: 45 mg/mL | [form ]
solid | [color ]
white | [InChI]
1S/C16H17BrN2.2ClH/c1-19(2)11-9-16(14-4-3-10-18-12-14)13-5-7-15(17)8-6-13;;/h3-10,12H,11H2,1-2H3;2*1H/b16-9-;; | [InChIKey]
CXGURXWCQYHDIR-ULPVBNQHSA-N | [SMILES]
Cl[H].Cl[H].[H]\C(CN(C)C)=C(/c1ccc(Br)cc1)c2cccnc2 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [Safety Statements ]
36 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Antidepressant;5-HT uptake inhibitor | [Uses]
Zimelidine dihydrochloride has been used as a serotonin transport inhibitor to study its inhibitory role in the uptake of exogenous serotonin by bipolar cells. | [Biochem/physiol Actions]
Zimelidine, an antidepressant, is a specific 5-hydroxytryptamine (5-HT) reuptake inhibitor, that can be used in treating phobic anxiety. It is very effective and can be tolerated well in elderly individuals. This serotonin transport inhibitor is less likely than other antidepressants to have cardiovascular side effects. Unlike other tricyclic antidepressants, Zimelidine might promote weight loss but not weight gain. |
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| Company Name: |
Sigma-Aldrich
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| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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