| Identification | Back Directory | [Name]
pholedrine sulphate | [CAS]
6114-26-7 | [Synonyms]
pholedrine sulphate
4-(2-(METHYLAMINO)PROPYL)PHENOL HEMISULFATE | [EINECS(EC#)]
228-083-0 | [Molecular Formula]
C20H32N2O6S | [MOL File]
6114-26-7.mol | [Molecular Weight]
428.543 |
| Hazard Information | Back Directory | [Originator]
Pholedrine Sulfate, ZYF Pharm Chemical | [Manufacturing Process]
100 g β-(methoxyphenyl)isopropylamine prepared, for example by reduction of p-methoxybenzylmethylketone with hydrogen and nickel catalyst in presence of ammonia or by Mannix's method, 250 ml ethanol and calculated quantity of solution of formaldehyde and 70 g activated aluminum shaving were heated for 6 hours by stirring. The mixture was filtered, the solvent was removed in vacuum and the residue was dissolved in ethanol contained hydrochloric acid. The prepared hydrochloride of β-(pmethoxyphenyl)isopropylmethylamine had MP: 174°C.
In practice it is usually used as sulfate. | [Therapeutic Function]
Sympathomimetic, Mydriatic, Analeptic, Vasopressor |
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| Company Name: |
Merck KGaA
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| Telephone: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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