| Identification | Back Directory | [Name]
PL-100 | [CAS]
612547-11-2 | [Synonyms]
PL-100
MX-100
PPL 100
PPL-100
MK-8122
N-[(5s)-5-{[(4-aminophenyl)sulfonyl](isobutyl)amino}-6-hydroxyhex Yl]-nα-(methoxycarbonyl)-β-phenyl-l-phenylalaninamide
N-[(1S)-1-[[[(5S)-5-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-6-hydroxyhexyl]amino]carbonyl]-2,2-diphenylethyl]carbamic acid methyl ester
Carbamic acid, N-[(1S)-1-[[[(5S)-5-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-6-hydroxyhexyl]amino]carbonyl]-2,2-diphenylethyl]-, methyl ester | [Molecular Formula]
C33H44N4O6S | [MDL Number]
MFCD12761284 | [MOL File]
612547-11-2.mol | [Molecular Weight]
624.791 |
| Hazard Information | Back Directory | [Uses]
PL-100 is a potent HIV-1 protease inhibitor with a Ki of 36 pM and an EC50 of 16 nM. PL-100 inhibits viral replication by suppressing HIV-1 protease activity and demonstrates excellent antiviral efficacy against drug-resistant HIV strains. PL-100 can be used in research on drug-resistant HIV disease[1]. | [References]
[1] Dandache S, et al. In vitro antiviral activity and cross-resistance profile of PL-100, a novel protease inhibitor of human immunodeficiency virus type 1. Antimicrob Agents Chemother. 2007 Nov;51(11):4036-43. DOI:10.1128/AAC.00149-07 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
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