| Identification | Back Directory | [Name]
9-DEOXY-9-METHYLENE PROSTAGLANDIN E2 | [CAS]
61263-32-9 | [Synonyms]
VKEJXDXJUFQESA-DLMPNJEASA-N
9-DEOXY-9-METHYLENE PROSTAGLANDIN E2
9-deoxy-9-methylene Prostaglandin E2
9-METHYLENE-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-OIC ACID
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-methylene-, (5Z,11α,13E,15S)- | [Molecular Formula]
C21H34O4 | [MDL Number]
MFCD00135214 | [MOL File]
61263-32-9.mol | [Molecular Weight]
350.49 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2) |
| Hazard Information | Back Directory | [Description]
9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2 . 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2. | [Uses]
9-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2. | [Definition]
ChEBI: 9-Deoxy-9-methylene-PGE2 is a long-chain fatty acid. | [storage]
Store at -20°C | [References]
[1] Bundy, et al. Synthesis and biological activity of 9-deoxo-9-methylene and related prostaglandins. Adv. Prostaglandin Thromboxane Res. 6, 355-363 (1980). |
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