| Identification | Back Directory | [Name]
Lignoceric Acid-d4 | [CAS]
61389-26-2 | [Synonyms]
Lignoceric Acid-d4
Tetracosanoic-3,3,5,5-d4 acidQ: What is
Tetracosanoic-3,3,5,5-d4 acid Q: What is the CAS Number of
Tetracosanoic-3,3,5,5-d4 acid | [Molecular Formula]
C24H48O2 | [MOL File]
61389-26-2.mol | [Molecular Weight]
368.65 |
| Hazard Information | Back Directory | [Uses]
Lignoceric acid-d4 (Tetracosanoic acid-d4) is deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2][1][2][3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. DOI:10.1002/jcp.28467
[3] J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). Eur J Biochem. 1977 Jan 3;72(1):41-7. DOI:10.1111/j.1432-1033.1977.tb11222.x |
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| Company Name: |
Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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