| Identification | Back Directory | [Name]
2-Chloroquinazoline | [CAS]
6141-13-5 | [Synonyms]
2-chloroquinazoline
Quinazoline, 2-chloro-
2-Chloroquinazoline(WX636001) | [Molecular Formula]
C8H5ClN2 | [MDL Number]
MFCD09959715 | [MOL File]
6141-13-5.mol | [Molecular Weight]
164.59 |
| Chemical Properties | Back Directory | [Melting point ]
108 °C(Solv: ligroine (8032-32-4)) | [Boiling point ]
250.0±13.0 °C(Predicted) | [density ]
1.349±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [form ]
solid | [pka]
0.22±0.30(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
2-chloroquinazoline is found to act as a versatile building block for the direct introduction of the 2-quinazolinyl moiety.
| [Preparation]
(1) ortho-aminobenzoic acid reacts with potassium cyanate to generate 2,4-quinazoline diones; and (2) the 2,4-quinazoline diones and a chlorinating agent undergo a chlorination reaction to generate the 2,4-dichloroquinazoline. |
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