| Identification | Back Directory | [Name]
2-Chloro-4-methylquinazoline | [CAS]
6141-14-6 | [Synonyms]
2-Chloro-4-methylquinazoline
Quinazoline, 2-chloro-4-methyl- | [Molecular Formula]
C9H7ClN2 | [MDL Number]
MFCD09998826 | [MOL File]
6141-14-6.mol | [Molecular Weight]
178.62 |
| Chemical Properties | Back Directory | [Boiling point ]
262.8±23.0 °C(Predicted) | [density ]
1.292±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [pka]
0.94±0.30(Predicted) | [Appearance]
White to yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
2-Chloro-4-methylquinazoline was prepared by reacting 4-methylquinazolin-2(3H)-one as starting material in the presence of phosphorus trichloride and hydrochloric acid, referring to the method of Example 27c. The reaction yield was 67% of the theoretical value, and the product was detected by thin layer chromatography (silica gel plate, unfolding agent was petroleum ether/ethyl acetate=7:3) with an Rf value of 0.81. | [References]
[1] Patent: US6200976, 2001, B1
[2] Chemical Communications, 2014, vol. 50, # 33, p. 4302 - 4304
[3] Patent: WO2005/123714, 2005, A1. Location in patent: Page/Page column 7 |
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| Company Name: |
SynAsst Chemical.
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| Telephone: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
| Company Name: |
NovoChemy Ltd.
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| Telephone: |
86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
| Company Name: |
Cool Pharm, Ltd
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| Telephone: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com.cn |
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