| Identification | Back Directory | [Name]
QUINIDINE HYDROCHLORIDE | [CAS]
6151-40-2 | [Synonyms]
QUINIDINE HYDROCHLORIDE
QUINIDINE HYDROCHLORIDE MONOHYDRATE
Quinidine monohydrate hydrochloride
Quinidine monohydrochloride monohydrate
QUINIDINE HYDROCHLORIDE ISO 9001：2015 REACH
QUINIDINE HYDROCHLORIDE MONOHYDRATE CRYSTALLINE
6μ-Methoxycinchonan-9-ol hydrochloride monohydrate
Quinidine hydrochloride monohydrate technical grade | [EINECS(EC#)]
628-688-3 | [Molecular Formula]
C20H24N2O2.ClH.H2O | [MDL Number]
MFCD00190162 | [MOL File]
6151-40-2.mol | [Molecular Weight]
378.9 |
| Chemical Properties | Back Directory | [Melting point ]
258-259 C | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (263.93 mM); Water: 2.5 mg/mL (6.60 mM) | [form ]
Solid | [color ]
White to off-white | [InChIKey]
SGVZDMWHXVXUBY-KAIFKDDSSA-N | [SMILES]
O.Cl.[H][C@@]1(C[C@@H]2CC[N@H]1C[C@@H]2C=C)[C@@H](O)c3ccnc4ccc(OC)cc34 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
20/21/22-36/37/38 | [Safety Statements ]
36-26 | [RIDADR ]
UN 2811 6.1/PG 3 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Antiarrhythmic;Heme polymerase inhibitor | [Uses]
Studied for pharmacological activity causing energy shifts from mitochondrial respiration to glycolysis1 | [Biochem/physiol Actions]
Class IA antiarrhythmic; potassium channel blocker. | [in vivo]
Direct application of Quinidine hydrochloride monohydrate on the sciatic nerve produces a dose-related decrease in amplitude at ascending somato-sensory evoked potential (SSEP) and descending compound muscle action potentials (CMAP) when comparing baseline with other time points, or when comparing the experimental left limb to the right contra-lateral glucose-treated limb. The latencies of SSEPs and CMAP potentials after Quinidine hydrochloride monohydrate applications are increased compare to baseline and the contralateral side[2]. | [IC 50]
Plasmodium |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|