| Identification | Back Directory | [Name]
Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]- | [CAS]
61848-66-6 | [Synonyms]
Nsc265460
Nsc 265460
Oxaliplatin System Suitability (25 mg)
Dichloro(1R,2R-cyclohexanediammine)platinum(II)
Cis-Dichloro-(1R)-trans-1,2-cyclohexanediaMine platinuM(Ⅱ)
Cis-Dichloro-(1R)-trans-1,2-cyclohexanediamine platinum(Ⅱ)
Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, (sp-4-2-(1R-trans))-
Platinum, dichloro(1,2-cyclohexanediamine-N,N')-, [sp-4-2-(1R-trans)]-
[SP-4-2-(1R-trans)]-(1,2-CyclohexanediaMine-N,N') DichloridoplatinuM(II)
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N') dichlorideplatinum(II)
Oxaliplatin System Suitability ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N'') dichloridoplatinu (1481306)
Oxaliplatin System Suitability (25 mg) ([SP-4-2-(1R-trans)]-(1,2-cyclohexanediamine-N,N') dichloridoplatinum(II)) | [Molecular Formula]
C6H12Cl2N2Pt | [MDL Number]
MFCD00058826 | [MOL File]
61848-66-6.mol | [Molecular Weight]
378.157 |
| Chemical Properties | Back Directory | [Melting point ]
>256°C (dec.) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly) | [form ]
Solid | [color ]
Yellow | [Major Application]
pharmaceutical (small molecule) | [InChI]
InChI=1/C6H12N2.2ClH.Pt/c7-5-3-1-2-4-6(5)8;;;/h5-8H,1-4H2;2*1H;/q-2;;;+4/p-2/t5-,6-;;;/s3 | [InChIKey]
UUERTZXRKZEANK-SIGUBHPQNA-L | [SMILES]
[Cl-][Pt+2]1(N[C@]2([H])CCCC[C@@]2([H])N1)[Cl-] |&1:3,9,r| |
| Hazard Information | Back Directory | [Uses]
[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N’) dichloridoplatinum(II) is an impurity of Oxiplatin (O845075), third generation platinum complex. An antitumor agent with activity against colorectal cancer. Cytotoxicity follows the formation of adducts with DNA. Antineoplastic. |
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