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619294-62-1

619294-62-1 Structure

619294-62-1 Structure
IdentificationBack Directory
[Name]

(E)-1-((3-Pentyl-1H-inden-1-ylidene)methyl)naphthalene
[CAS]

619294-62-1
[Synonyms]

JWH 176
1-[(E)-(3-pentylinden-1-ylidene)methyl]naphthalene
(E)-1-((3-Pentyl-1H-inden-1-ylidene)methyl)naphthalene
1-[(E)-(3-Pentyl-1H-inden-1-ylidene)methyl]naphthalene
Naphthalene, 1-[(E)-(3-pentyl-1H-inden-1-ylidene)methyl]-
[Molecular Formula]

C25H24
[MDL Number]

MFCD20926229
[MOL File]

619294-62-1.mol
[Molecular Weight]

324.46
Chemical PropertiesBack Directory
[Boiling point ]

487.8±15.0 °C(Predicted)
[density ]

1.085±0.06 g/cm3(Predicted)
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

JWH 176 is a cannabimimetic indene hydrocarbon with high affinity for the central cannabinoid (CB1) receptor (Ki = 26 nM). It was originally prepared to examine the roles of hydrogen bonding involving the carbonyl group and aromatic stacking in CB1 receptor docking studies. This product is intended for forensic and research applications.
[Uses]

JWH 176 is a new cannabimimetic indole that showed interactions with the CB1 Cannabinoid receptor.
[References]

[1] J W HUFFMAN  L W P. Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes.[J]. Current medicinal chemistry, 2005, 12 12: 1395-1411. DOI: 10.2174/0929867054020864
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