| Identification | Back Directory | [Name]
ETHYL ACETOACETATE (3-13C) | [CAS]
61973-42-0 | [Synonyms]
ETHYL ACETOACETATE (3-13C)
ETHYL ACETOACETATE-3-13C, 99 ATOM % 13C | [Molecular Formula]
C6H10O3 | [MDL Number]
MFCD00083953 | [MOL File]
61973-42-0.mol | [Molecular Weight]
131.15 |
| Chemical Properties | Back Directory | [Melting point ]
-43 °C (lit.) | [Boiling point ]
181 °C (lit.) | [density ]
1.037 g/mL at 25 °C | [refractive index ]
n20/D 1.419(lit.) | [Fp ]
84 °C |
| Hazard Information | Back Directory | [Uses]
Ethyl acetoacetate-13C is the 13C labeled Ethyl acetoacetate[1]. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[2][3][4]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[5]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Rao M.Uppu, et al. Enantioselective catalytic asymmetric hydrogenation of ethyl acetoacetate in room temperature ionic liquids. Biochemical and Biophysical Research Communications. 1996 Dec; 229(3):764-769.
[3] Leo F. Salter, et al. A dual‐frequency Belousov Zhabotinskii oscillating reaction with ethyl acetoacetate as organic substrate. substrate. International Journal of Chemical Kinetics. 1982. 14(8), 815–821.
[4] Iqbal S, et al. 2-Oxo-1,2,3,4-tetrahydropyrimidines Ethyl Esters as Potent β- Glucuronidase Inhibitors: One-pot Synthesis, In vitro and In silico Studies. Med Chem. 201814(8):818-830. DOI:10.2174/1573406414666180525105325
[5] Horne SM, et al. Acetoacetate and ethyl acetoacetate as novel inhibitors of bacterial biofilm. Lett Appl Microbiol. 2018 Apr66(4):329-339. DOI:10.1111/lam.12852 |
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