| Identification | Back Directory | [Name]
chlormerodrin | [CAS]
62-37-3 | [Synonyms]
Oricur
Katonil
Merilid
Mercoral
Percapyl
ProMeran
ProMerane
Mercardox
Mercloran
Merculest
Neogidrin
Neohydrin
NSC 19911
Chlormeroprin
Chloromeridin
Chlormerodrine
Diurone【diuretic】
KYXYMFPMUKDJJI-UHFFFAOYSA-M
3-Chloromercuri-2-methoxypropylurea
[3-(Chloromercuri)-2-methoxypropyl]urea
MERCURY,CHLORO(2-METHOXY-3-UREIDOPROPYL)-
[3-(carbamoylamino)-2-methoxypropyl]-chloromercury
[3-[(Aminocarbonyl)amino]-2-hydroxypropyl]chloromercury | [EINECS(EC#)]
200-530-4 | [Molecular Formula]
C5H11ClHgN2O2 | [MDL Number]
MFCD00025457 | [MOL File]
62-37-3.mol | [Molecular Weight]
367.197 |
| Hazard Information | Back Directory | [Originator]
Neohydrin,Lakeside,US,1952 | [Uses]
Chlormerodrin is a sulfhydryl blocking agent; using NK cells, particularly CAR-modified NK cells, for producing induced cellular vesicles (ICVs) loaded with chemotherapeutic agent(s) for cancer therapy. | [Definition]
ChEBI: Chlormerodrin is urea in which one of the hydrogens is substituted by a 3-chloromercury-2-methoxyprop-1-yl group. It was formerly used as a diuretic, but more potent and less toxic drugs are now available. Its radiolabelled ((197)Hg, (203)Hg) forms were used in diagnostic aids in renal imaging and brain scans. It has a role as a diuretic and a diagnostic agent. It is an organomercury compound and a member of ureas. | [Manufacturing Process]
To a refluxing solution of 100 g of allyl urea and 600 ml of absolute methanol
there was added with stirring a suspension of 319 g of mercuric acetate and
600 ml of absolute methanol and 60 ml of glacial acetate acid; complete
solution resulted. After 6 hours of refluxing, the solution was cooled and
clarified by filtration. To this solution there were added 50 g of sodium
chloride and 240 ml of water. After a short time a heavy white precipitate
settled out. This precipitate, which was 3-chloromercuri-2-methoxypropylurea, was filtered, washed and dried. | [Brand name]
Mercloran (Parke-Davis); Neohydrin
(Marion Merrell Dow). | [Therapeutic Function]
Diuretic |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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