| Identification | Back Directory | [Name]
2-aminopropanediamide | [CAS]
62009-47-6 | [Synonyms]
NSC 75208
Aminomalonamide
favipiravir-001
2-Aminopropandiamid
2-aminopropanediamide
2-azanylpropanediamide
PropanediaMide, 2-aMino-
2-Aminopropane-1,3-diamide
amino-malonic acid diamide
Amino-malonsaeure-diamid,Hydrojodid
2-aminopropanediamide ISO 9001：2015 REACH | [EINECS(EC#)]
263-370-4 | [Molecular Formula]
C3H7N3O2 | [MDL Number]
MFCD00015932 | [MOL File]
62009-47-6.mol | [Molecular Weight]
117.107 |
| Chemical Properties | Back Directory | [Melting point ]
180-185°C | [Boiling point ]
410.1±40.0 °C(Predicted) | [density ]
1.399±0.06 g/cm3(Predicted) | [storage temp. ]
-20?C Freezer | [solubility ]
DMSO (Sparingly), Methanol (Sparingly) | [form ]
Solid | [pka]
9.87±0.70(Predicted) | [color ]
Pale Yellow to Beige | [InChI]
InChI=1S/C3H7N3O2/c4-1(2(5)7)3(6)8/h1H,4H2,(H2,5,7)(H2,6,8) | [InChIKey]
GFQBSQXXHYLABK-UHFFFAOYSA-N | [SMILES]
C(N)(=O)C(N)C(N)=O | [CAS DataBase Reference]
62009-47-6 |
| Hazard Information | Back Directory | [Chemical Properties]
Beige Solid | [Uses]
2-aminopropanediamide is a reagent used in the synthesis of Imidazole derivatives.
| [Synthesis]
The general procedure for the synthesis of 2-aminomalonamide from diethyl aminomalonate is as follows: 17.5 g of diethyl 2-aminomalonate and 22 g of 50% aqueous ammonium chloride were accurately weighed, mixed, and then heated at reflux for 2 h at 100 °C. The reaction was completed by filtration. After completion of the reaction, the reaction mixture was cooled to room temperature and the solid product was separated by filtration. The resulting solid was dried with hot air at 60 °C for 8 h. A white crystalline powder 2-aminomalonamide 10.2 g was obtained in 87% yield. | [References]
[1] Patent: WO2007/144686, 2007, A1. Location in patent: Page/Page column 129-130
[2] Patent: CN108250104, 2018, A. Location in patent: Paragraph 0016; 0017; 0018; 0019
[3] Patent: EP2196460, 2010, A1. Location in patent: Page/Page column 5; 6
[4] Journal of the American Chemical Society, 1949, vol. 71, p. 78,79, 80 |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
SynAsst Chemical.
|
| Telephone: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
|