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62252-25-9

62252-25-9 Structure

62252-25-9 Structure
IdentificationBack Directory
[Name]

4-chloro-3-methoxy-7-nitroisochromen-1-one
[CAS]

62252-25-9
[Synonyms]

4-chloro-3-methoxy-7-nitroisochromen-1-one
4-Chloro-3-methoxy-7-nitro-1H-isochromen-1-one
1H-2-Benzopyran-1-one, 4-chloro-3-methoxy-7-nitro-
[Molecular Formula]

C10H6ClNO5
[MDL Number]

MFCD25965461
[MOL File]

62252-25-9.mol
[Molecular Weight]

255.61
Chemical PropertiesBack Directory
[Melting point ]

115 °C
[Boiling point ]

455.1±45.0 °C(Predicted)
[density ]

1.57±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

Caspase-3-IN-2 (Compound 4d) is the inhibitor for α-Chymotrypsin. Caspase-3-IN-2 also exhibits inhibitory activity against HIV protease and caspase 3 with an inhibition rate of 57% and 51% at 100 μM[1].
[References]

[1] Bihel F, et al., Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new beta-amyloid peptide production inhibitors and their activities on various classes of protease. Bioorg Med Chem. 2003 Jul 17;11(14):3141-52. DOI:10.1016/s0968-0896(03)00235-9
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