ChemicalBook--->CAS DataBase List--->6237-31-6

6237-31-6

6237-31-6 Structure

6237-31-6 Structure
IdentificationBack Directory
[Name]

C175
[CAS]

6237-31-6
[Synonyms]

C175
C-175
C 175
[Molecular Formula]

C19H23ClN4O2
[MOL File]

6237-31-6.mol
[Molecular Weight]

374.87
Chemical PropertiesBack Directory
[Melting point ]

224-225 °C
Hazard InformationBack Directory
[Uses]

C 175 is a nitroacridine derivative with antitumor activity. C 175 inhibits the growth of HeLa cells monolayer (ED50=0.49 μM)[1].
[References]

[1] Pawlak K, et al. The mode of action of cytotoxic and antitumor 1-nitroacridines. I. The 1-nitroacridines do not exert their cytotoxic effects by physicochemical binding with DNA[J]. Chemico-Biological Interactions, 1983, 43(2): 131-149. DOI:10.1016/0009-2797(83)90092-3
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