| Identification | Back Directory | [Name]
Methyl [4,6-diaMino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidin-5-yl]carbaMate | [CAS]
625115-52-8 | [Synonyms]
Nelociguat
BAY 60-4552
Riociguat-4
Desmethyl Riociguat
N-Desmethyl Riociguat
methyl (4,6-diamino-2
Riociguat Impurity NK1
Riociguat N-Desmethyl Impurity
Methyl [4,6-diaMino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidin-5-yl]carbaMate
methyl N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]carbamate
Name: Methyl [4,6-diaMino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyriMidin-5-yl]carbaMate
N-Desmethyl Riociguat/Methyl(4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
Carbamic acid, N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-, methyl ester
Riociguat Impurity 19/N-Desmethyl Riociguat/Methyl(4,6-diamino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-5-yl)carbamate
Desmethyl RiociguatQ: What is
Desmethyl Riociguat Q: What is the CAS Number of
Desmethyl Riociguat Q: What is the storage condition of
Desmethyl Riociguat Q: What are the applications of
Desmethyl Riociguat | [Molecular Formula]
C19H17FN8O2 | [MDL Number]
MFCD22741546 | [MOL File]
625115-52-8.mol | [Molecular Weight]
408.39 |
| Chemical Properties | Back Directory | [Melting point ]
>196oC (dec.) | [Boiling point ]
533.3±50.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly, Heated), Methanol (Very Slightly, Heated) | [form ]
Solid | [pka]
10.68±0.70(Predicted) | [color ]
Light Brown |
| Hazard Information | Back Directory | [Uses]
N-Desmethyl-riociguat, is a complex that is part affiliated with potent oral stimulator for the treatment of pulmonary hypertension. | [Definition]
ChEBI: Nelociguat is a member of the class of pyrazolopyridines that is 1H-pyrazolo[3,4-b]pyridine which is substituted by a 2-fluorobenzyl and 4,6-diamino-5-[(methoxycarbonyl)amino]pyrimidin-2-yl groups at positions 1 and 3, respectively. It is an active metabolite of riociguat and a soluble guanylate cyclase stimulator developed by Bayer for the treatment of erectile dysfunction and heart failure. It has a role as a soluble guanylate cyclase activator, an antihypertensive agent, a drug metabolite and a vasodilator agent. It is a pyrazolopyridine, a member of monofluorobenzenes, a carbamate ester and an aminopyrimidine. |
|
| Company Name: |
Alputon Inc.
|
| Telephone: |
021-60753308-14013 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList13466/0_EN.htm |
| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
|