| Identification | Back Directory | [Name]
1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE | [CAS]
625458-06-2 | [Synonyms]
UCCF853
UCCF-853
UCCF 853
1-(3-CHLOROPHENYL)-5-TRIFLUOROMETHYL-3-HYDROBENZIMIDAZOL-2-ONE
2H-BENZIMIDAZOL-2-ONE, 1-(3-CHLOROPHENYL)-1,3-DIHYDRO-5-(TRIFLUOROMETHYL)- | [Molecular Formula]
C14H8ClF3N2O | [MDL Number]
MFCD09054670 | [MOL File]
625458-06-2.mol | [Molecular Weight]
312.67 |
| Hazard Information | Back Directory | [Description]
UCCF-853 is an activator of the CFTR Cl- channel which may be useful for therapy of cystic fibrosis. | [Uses]
UCCF-853 is a CFTR modulator[1]. | [References]
[1] Nicoletta Pedemonte, et al. Influence of cell background on pharmacological rescue of mutant CFTR. Am J Physiol Cell Physiol. 2010 Apr;298(4):C866-74. DOI:10.1152/ajpcell.00404.2009 |
|
|