| Identification | Back Directory | [Name]
2-Naphthalenesulfonic acid, 6,6'-(carbonyldiimino)bis[4-hydroxy- | [CAS]
6266-54-2 | [Synonyms]
NSC37204
NSC-37204
NSC 37204
2-Naphthalenesulfonic acid, 6,6'-(carbonyldiimino)bis[4-hydroxy- | [Molecular Formula]
C21H16N2O9S2 | [MDL Number]
MFCD30556435 | [MOL File]
6266-54-2.mol | [Molecular Weight]
504.49 |
| Hazard Information | Back Directory | [Description]
SM27 is an inhibitor of Fibroblast Growth Factor 2 (FGF2). | [Uses]
SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation[1]. | [References]
[1] Pagano K, et al., Direct and allosteric inhibition of the FGF2/HSPGs/FGFR1 ternary complex formation by an antiangiogenic, thrombospondin-1-mimic small molecule. PLoS One. 2012;7(5):e36990. DOI:10.1371/journal.pone.0036990 |
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