| Identification | Back Directory | [Name]
2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy-(2,3-dihydroxypropoxy)phosphinic acid | [CAS]
62700-69-0 | [Synonyms]
PhosphoLipid-DOPG
dioleoyl phosphatidylglycerol
Dioleoyl phosphatidylglycerol sodium salt
L-α-Phosphatidyl-DL-glycerol,dioleyl,sodium salt
2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy-(2,3-dihydroxypropoxy)phosphinic acid
[3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (E)-octadec-9-enoate
9-Octadecenoic acid (9Z)-, 1,1'-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester | [Molecular Formula]
C42H79O10P | [MOL File]
62700-69-0.mol | [Molecular Weight]
775.04 |
| Hazard Information | Back Directory | [Uses]
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) [1]. | [Definition]
ChEBI: A phosphatidylglycerol in which the phosphatidyl acyl groups are both oleoyl. | [References]
[1] Chang L, et al. Low-dose dioleoylphosphatidylglycerol (DOPG) inhibits heat shock protein B4 (HSPB4)-induced activation of toll-like receptor 2 (TLR2) in a reporter cell line. Investigative Ophthalmology & Visual Science, 2020, 61(7): 357-357. |
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