| Identification | Back Directory | [Name]
Levonadifloxacin Arginine Salt | [CAS]
627891-34-3 | [Synonyms]
WCK771
WCK-771
WCK771A
WCK 771
WCK 771A
WCK-771A
Levonadifloxacin Arginine Salt |
| Hazard Information | Back Directory | [Uses]
Levonadifloxacin (arginine) hydrate is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin (arginine) hydrate shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes[1]. | [References]
[1] Dubois J, et al. Levonadifloxacin (WCK 771) exerts potent intracellular activity against Staphylococcus aureus in THP-1 monocytes at clinically relevant concentrations. J Med Microbiol. 2019 Dec;68(12):1716-1722. DOI:10.1099/jmm.0.001102
[2] Bhagwat SS, et al. In Vivo Pharmacokinetic/Pharmacodynamic Targets of Levonadifloxacin against Staphylococcus aureus in a Neutropenic Murine Lung Infection Model. Antimicrob Agents Chemother. 2019 Jul 25;63(8):e00909-19. DOI:10.1128/AAC.00909-19 |
|
|