| Identification | Back Directory | [Name]
DL-A-HYDROXYSTEARIC ACID | [CAS]
629-22-1 | [Synonyms]
DL-A-HYDROXYSTEARIC ACID
dl-α-hydroxystearic acid
DL-2-Hydroxystearic acid
Octadecanoic acid,2-hydroxy-
DL-alpha-Hydroxystearic acid >=99%
2-Hydroxy stearic acid|||DL-2-Hydroxystearic acid | [Molecular Formula]
C18H36O3 | [MDL Number]
MFCD00046526 | [MOL File]
629-22-1.mol | [Molecular Weight]
300.48 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
Chloroform:Methanol (5:1): Soluble | [form ]
A solid | [Appearance]
White to off-white Solid | [biological source]
synthetic (organic) |
| Hazard Information | Back Directory | [Description]
2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U. armoricana. It reduces growth of Ehrlich ascites tumor (EAT) cells in vitro when used at a concentration of 100 μM. Levels of 2-hydroxy stearic acid are elevated in human joint synovial fluid after ankle fracture and in patients with Buruli ulcer disease. [Matreya, LLC. Catalog No. 1707] | [Uses]
2-Hydroxystearic Acid can be used to study the differential effects of post-?weaning diet and maternal obesity on mouse liver and brain metabolomes. | [Definition]
ChEBI: A long-chain fatty acid that is stearic (octadecanoic) acid substituted at position 2 by a hydroxy group. | [References]
[1] MELHA KENDEL. Lipid Composition, Fatty Acids and Sterols in the Seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): An Analysis from Nutritional, Chemotaxonomic, and Antiproliferative Activity Perspectives.[J]. Marine Drugs, 2015, 13 9: 5606-5628. DOI: 10.3390/md13095606
[2] ELIZABETH M. LEIMER. Lipid profile of human synovial fluid following intra-articular ankle fracture[J]. Journal of Orthopaedic Research?, 2016, 35 3: 657-666. DOI: 10.1002/jor.23217
[3] FATOUMATA NIANG. Metabolomic profiles delineate mycolactone signature in Buruli ulcer disease.[J]. Scientific Reports, 2015, 5 1: 17693. DOI: 10.1038/srep17693
[4] K KUSUMOTO. Effects of ethyl-esterization, chain-lengths, unsaturation degrees, and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids.[J]. Experimental oncology, 2007, 29 2: 106-110.
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