| Identification | Back Directory | [Name]
stilbene-4,4'-dicarbonitrile | [CAS]
6292-62-2 | [Synonyms]
stilbene-4,4'-dicarbonitrile
4,4-DICYANOSTILBENE(WXG00901)
4,4'-(1,2-Ethenediyl)bisbenzonitrile
Benzonitrile, 4,4'-(1,2-ethenediyl)bis- | [EINECS(EC#)]
228-548-8 | [Molecular Formula]
C16H10N2 | [MDL Number]
MFCD00438701 | [MOL File]
6292-62-2.mol | [Molecular Weight]
230.26 |
| Chemical Properties | Back Directory | [Melting point ]
278 °C | [Boiling point ]
445.0±34.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(E/Z)-4,4'-Dicyanostilbene is the isomer of 4,4'-Dicyanostilbene (HY-W112166A), and can be used as an experimental control. 4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA)[1]. | [References]
[1] Kyei-Baffour K, et, al. Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites. Bioorg Med Chem. 2020 Oct 1;28(19):115678. DOI:10.1016/j.bmc.2020.115678 |
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