| Identification | Back Directory | [Name]
2-ethoxy-5-methylaniline | [CAS]
6331-70-0 | [Synonyms]
6-Ethoxy-m-toluidine
5-Methyl-o-phenetidine
6-Ethoxy-3-methylaniline
2-Ethoxy-5-methyl-anilin
2-ethoxy-5-methylbenzenamine
o-Amino-p-toluene ethyl ether
Benzenamine,2-ethoxy-5-methyl-
(2-ethoxy-5-methyl-phenyl)amine
2-ethoxy-5-methylaniline Basic information | [EINECS(EC#)]
228-708-7 | [Molecular Formula]
C9H13NO | [MDL Number]
MFCD00035775 | [MOL File]
6331-70-0.mol | [Molecular Weight]
151.21 |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 2-amino-4-methylphenylethyl ether from 4-ethoxy-3-nitrotoluene: A suspension formed by 1-ethoxy-4-methyl-2-nitrobenzene (2.71 g) with 10% palladium-carbon catalyst (0.27 g) in anhydrous tetrahydrofuran (40 mL) was stirred at room temperature. After 25.5 hours of reaction in a hydrogen atmosphere, the reaction mixture was filtered through cellulose powder. The filtrate was concentrated under reduced pressure and dried to give 2.26 g of 2-amino-4-methylphenylethyl ether as a dark brown solid in 100% yield. | [References]
[1] Patent: EP1764360, 2007, A1. Location in patent: Page/Page column 106
[2] Justus Liebigs Annalen der Chemie, 1883, vol. 217, p. 172
[3] Gazzetta Chimica Italiana, 1969, vol. 99, p. 397 - 410 |
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