| Identification | Back Directory | [Name]
Tylosin, 3-acetate 4B-(3-methylbutanoate) | [CAS]
63409-12-1 | [Synonyms]
TYLVALOSIN
Tylvalosin (>
Tylvalosin (>90%)
Aivlosin，Tylvalosin
ACETYLISOVALERYLTYLOSIN
KCJJINQANFZSAM-XRMHJPERSA-N
3-acetyl-4''-isovaleryltylosin
3-O-Acetyl-4''-O-isovaleryltylosin
Acetylisovaleryltylosin/ tylvalosin
Tylosin, 3-acetate 4B-(3-methylbutanoate)
Tyrosine [antibiotic]3-acetate 4''-(3-methylbutanoate) | [EINECS(EC#)]
264-132-2 | [Molecular Formula]
C53H87NO19 | [MDL Number]
MFCD30720279 | [MOL File]
63409-12-1.mol | [Molecular Weight]
1042.25 |
| Chemical Properties | Back Directory | [Melting point ]
>105°C (dec.) | [Boiling point ]
1005.4±65.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.06±0.70(Predicted) | [color ]
Off-White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
Tylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria. | [in vivo]
Tylvalosin tartrate (160 mg/kg; po; 7 d) can reduce the stress state of pigs during the immunization process with PRRSV inactivated vaccine and improve the health of pig[5].
| Animal Model: | PRRSV-free commercial breed piglets[5] | | Dosage: | 800 mg/kg Aivlosin (20% Tylvalosin Tartrate Premix) | | Administration: | po; 7-14 days | | Result: | Attenuated the increase in total white blood cells induced by immunization at day one post-immunization (DPI) and induced an increase in monocyte counts after seven DPI.
Attenuate the reduction in the percentage of CD8+ T cells induced by PRRSV-inactivated vaccine immunization at seven DPI.
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