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63476-70-0

63476-70-0 Structure

63476-70-0 Structure
IdentificationBack Directory
[Name]

Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
[CAS]

63476-70-0
[Synonyms]

NiCur
T9129
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
3,3'-((2-Oxocyclohexane-1,3-diylidene)bis(methanylylidene))dibenzonitrile
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
Benzonitrile, 3,3''-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
Benzonitrile, 3,3''-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI), 10 mM in DMSO
Benzonitrile, 3,3' [(2 oxo 1,3 cyclohexanediylidene)dimethylidyne]bis (9CI),Benzonitrile, 3,3'[(2oxo1,3cyclohexanediylidene)dimethylidyne]bis (9CI)
[Molecular Formula]

C22H16N2O
[MOL File]

63476-70-0.mol
[Molecular Weight]

324.38
Chemical PropertiesBack Directory
[Melting point ]

175-178 °C
[Boiling point ]

573.9±50.0 °C(Predicted)
[density ]

1.22±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

(E/Z)-NiCur is the active isomer of NiCur (HY-139149). (E/Z)-NiCur is a potent CBP histone acetyltransferase (HAT) inhibitor[1].
[References]

[1] Vincek AS, et al. Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3. Molecules. 2018;23(8):1930. Published 2018 Aug 2. DOI:10.3390/molecules23081930
Spectrum DetailBack Directory
[Spectrum Detail]

Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)(63476-70-0)1HNMR
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