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63555-63-5

63555-63-5 Structure

63555-63-5 Structure
IdentificationBack Directory
[Name]

C3A (70-77)
[CAS]

63555-63-5
[Synonyms]

C3a
ASHLGLAR
C3A (70-77)
complement 3a (70-77)
Complement C3a, (70-77)
ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG
ANAPHYLATOXIN C3A FRAGMENT 70-77
H-ALA-SER-HIS-LEU-GLY-LEU-ALA-ARG-OH
alanine-serine-histidine-leucine-glycine-leucine-alanine-
L-Arginine, L-alanyl-L-seryl-L-histidyl-L-leucylglycyl-L-leucyl-L-alanyl-
C3a (70-77) trifluoroacetate salt H-Ala-Ser-His-Leu-Gly-Leu-Ala-Arg-OH trifluoroacetate salt
[Molecular Formula]

C35H61N13O10
[MDL Number]

MFCD00133055
[MOL File]

63555-63-5.mol
[Molecular Weight]

823.94
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Predicted)
[storage temp. ]

−20°C
[solubility ]

Soluble in DMSO
[pka]

3.34±0.10(Predicted)
[Sequence]

Ala-Ser-His-Leu-Gly-Leu-Ala-Arg
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a.
[Biological Activity]

C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a and exhibits C3a specificity and 1 to 2% biological activity.
[in vitro]

The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD.
[target]

Complement system

[storage]

Store at -20°C
[References]

[1] Payan DG, et al. Modulation of human lymphocyte function by C3a and C3a(70-77). J Exp Med. 1982 Sep 1;156(3):756-65. DOI:10.1084/jem.156.3.756
[2] Caporale LH, et al. The active site of C3a anaphylatoxin. J Biol Chem. 1980 Nov 25;255(22):10758-63. PMID:6968751
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